No clear link ties acetaminophen in pregnancy to autism: Review

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(NewsNation) — A caller review has recovered nary wide nexus betwixt taking paracetamol, besides known arsenic acetaminophen, during gestation and a child's hazard of processing autism oregon ADHD.

The findings, published Sunday successful the BMJ, travel aft President Donald Trump warned that using Tylenol during pregnancy can origin autism successful children. Trump’s assertion is unproven and lacks technological evidence.

Researchers from the University of Liverpool examined 9 systematic reviews covering 40 observational studies connected paracetamol usage successful gestation and neurodevelopmental outcomes successful children. They concluded that the wide prime of grounds connecting paracetamol to neurodevelopmental disorders is "low to critically low."

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"We person shown that based connected existent evidence, determination is nary wide nexus betwixt women taking paracetamol during gestation and a diagnosis of autism oregon ADHD successful their children," said survey pb and University of Liverpool prof Shakila Thangaratinam. "The findings should assistance healthcare professionals springiness evidence-based proposal to women, and reassure mothers astir the usage of paracetamol during gestation if indicated.”

The reappraisal recovered immoderate associations reported successful earlier studies were apt influenced by familial and biology factors shared wrong families, specified arsenic parental intelligence wellness oregon lifestyle.

Researchers noted that lone 2 studies decently adjusted for family-related factors, and erstwhile they did, immoderate evident transportation betwixt acetaminophen and developmental disorders disappeared oregon was importantly reduced.

While researchers admit that much high-quality studies are needed, they accent that the existent assemblage of grounds does not enactment paracetamol usage successful pregnancy.

Trump’s informing connected Tylenol during pregnancy

Trump has urged large women not to instrumentality acetaminophen — 1 of the astir wide utilized medications successful the satellite — for symptom alleviation due to the fact that of a imaginable hazard of autism, contempt nary caller grounds proving the cause straight causes it.  

Acetaminophen has been seen arsenic the safest symptom medicine for large women to take.

Both the World Health Organization and the European Union have refuted Trump’s assertion that acetaminophen whitethorn origin conditions similar autism and ADHD erstwhile taken by large women. The FDA acknowledged that “a causal narration has not been established” successful nationalist statements pursuing Trump’s archetypal plea.

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Medical organizations person besides backed acetaminophen arsenic harmless for large women, including some the American College of Obstetricians and Gynecologists and the Society for Maternal-Fetal Medicine.

However, Trump and Health and Human Services Secretary Robert F. Kennedy Jr. said past period that the FDA would statesman updating the statement connected acetaminophen and notifying physicians that Tylenol “can beryllium associated with a precise accrued hazard of autism.”  

Tylenol maker Kenvue called on the FDA to propulsion backmost connected the projected information statement change. The existent label instructs radical who are large oregon breastfeeding to “ask a wellness nonrecreational earlier use.” 

The Hill contributed to this report.

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